The Promise of Single-cell Technology in Providing New Insights into the Molecular Heterogeneity and Management of Acute Lymphoblastic Leukemia
- Creator: Pearson, Holly C. L. , Hunt, Kooper V. , Trahair, Toby N. , Lock, Richard B. , Lee, Heather J. , de Bock, Charles E.
- Resource Type: journal article
- Date: 2022
Evaluating nuclear translocation of surface receptors: recommendations arising from analysis of CD44
- Creator: Thorne, Rick F. , Wang, Yan , Zhang, Yan , Jing, Xueli , Zhang, Xu Dong , de Bock, Charles E. , Oliveira, Camila S.
- Resource Type: journal article
- Date: 2020
FAT1 cadherin controls neuritogenesis during NTera2 cell differentiation
- Creator: Ahmed, Abdulrzag F. , de Bock, Charles E. , Sontag, Estelle , Hondermarck, Hubert , Lincz, Lisa F. , Thorne, Rick F.
- Resource Type: journal article
- Date: 2019
T-cell acute lymphoblastic leukemia express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development
- Creator: de Bock, Charles E. , Down, Michelle , Baidya, Kinsha , Sweron, Bram , Boyd, Andrew W. , Fiers, Mark , Burns, Gordon F. , Molloy, Timothy J. , Lock, Richard B. , Soulier, Jean , Taghon, Tom , Van Vlierberghe, Pieter , Cools, Jan , Holst, Jeff , Thorne, Rick F.
- Resource Type: journal article
- Date: 2019
Protein interaction screening identifies SH3RF1 as a new regulator of FAT1 protein levels
- Creator: de Bock, Charles E. , Hughes, Michael R. , Snyder, Kimberly , Alley, Steven , Sadeqzadeh, Elham , Dun, Matt D. , McNagny, Kelly M. , Molloy, Timothy J. , Hondermarck, Hubert , Thorne, Rick F.
- Resource Type: journal article
- Date: 2017
FAT1 cadherin acts upstream of Hippo signalling through TAZ to regulate neuronal differentiation
- Creator: Ahmed, Abdulrzag F. , de Bock, Charles E. , Lincz, Lisa F. , Pundavela, Jay , Zouikr, Ihssane , Sontag, Estelle , Hondermarck, Hubert , Thorne, Rick F.
- Resource Type: journal article
- Date: 2015
A soluble form of the giant cadherin Fat1 is released from pancreatic cancer cells by ADAM10 mediated ectodomain shedding
- Creator: Wojtalewicz, Nathalie , Sadeqzadeh, Elham , Thorne, Rick F. , Schwarte-Waldhoff, Irmgard , Weiß, Jakob V. , Tehrani, Mahnaz Moradian , Klein-Scory, Susanne , Hahn, Stephan , Schmiegel, Wolff , Warnken, Uwe , Schnölzer, Martina , de Bock, Charles E.
- Resource Type: journal article
- Date: 2014
FAT1 cadherin is multiply phosphorylated on its ectodomain but phosphorylation is not catalysed by the four-jointed homologue
- Creator: Sadeqzadeh, Elham , de Bock, Charles E. , O'Donnell, Maureen R. , Timofeeva, Anna , Burns, Gordon F. , Thorne, Rick F.
- Resource Type: journal article
- Date: 2014
Furin processing dictates ectodomain shedding of human FAT1 cadherin
- Creator: Sadeqzadeh, Elham , de Bock, Charles E. , Wojtalewicz, Natalie , Holt, Janet E. , Smith, Nathan D. , Dun, Matthew D. , Schwarte-Waldhoff, Irmgard , Thorne, Rick F.
- Resource Type: journal article
- Date: 2014
Macrophage migration inhibitory factor engages PI3K/Akt signalling and is a prognostic factor in metastatic melanoma
- Creator: Oliveira, Camila S. , de Bock, Charles E. , Molloy, Timothy J. , Sadeqzadeh, Elham , Geng, Xin Yan , Hersey, Peter , Zhang, Xu Dong , Thorne, Rick F.
- Resource Type: journal article
- Date: 2014
Sleeping giants: emerging roles for the Fat cadherins in health and disease
- Creator: Sadeqzadeh, Elham , de Bock, Charles E. , Thorne, Rick F.
- Resource Type: journal article
- Date: 2014
Fat1 cadherin provides a novel minimal residual disease marker in acute lymphoblastic leukemia
- Creator: Ardjmand, Alireza , de Bock, Charles E. , Shahrokhi, Somayeh , Lincz, Lisa F. , Boyd, Andrew W. , Burns, Gordon F. , Thorne, Rick F.
- Resource Type: journal article
- Date: 2013
PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma
- Creator: Ye, Yan , Jin, Lei , Tay, Kwang Hong , Tseng, Hsin-Yi , Guo, Su Tang , de Bock, Charles E. , Jiang, Chen Chen , Wang, Chun Yang , Wu, Mian , Zhang, Lie Jie , Hersey, Peter , Scolyer, Richard A. , Wilmott, James S. , Zhang, Xu Dong , Hu, Wang Lai , Yosufi, Benafsha , Thorne, Rick F. , Liu, Tao , Rizos, Helen , Yan, Xu Guang , Dong, Li
- Resource Type: journal article
- Date: 2013
Dual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein products
- Creator: Sadeqzadeh, Elham , de Bock, Charles E. , Boyd, Andrew W. , Burns, Gordon F. , Thorne, Rick F. , Zhang, Xu Dong , Shipman, Kristy L. , Scott, Naomi M. , Song, Chaojun , Yeadon, Trina , Oliveira, Camila S. , Jin, Boquan , Hersey, Peter
- Resource Type: journal article
- Date: 2011